P69. Ki-67 auto-antibodies in colorectal cancer patients
نویسندگان
چکیده
منابع مشابه
Comparison of Ki-67 equivalent antibodies.
AIMS To compare commercially available Ki-67 equivalent antibodies with regard to qualitative and quantitative immunohistochemical staining characteristics. METHODS The following antibodies were used: monoclonal MIB-1 (Immunotech), monoclonal MM1 (Novocastra), polyclonal NCL-Ki-67p (Novocastra), and polyclonal Rah Ki-67 (Dako). All immunostainings were evaluated in squamous epithelium from fo...
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BACKGROUND Ki67 labeling index (Ki67 LI), the percentage Ki67 immunoreactive cells, is a measure of tumor proliferation, with important clinical relevance in breast cancer, and it is extremely important to standardize its evaluation. AIM To test the efficacy of computer assisted image analysis (CAIA) applied to completely digitized slides and to assess its feasibility in routine practice and ...
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Background: Inflammatory bowel disease unclassified (IBDU) is considered to be an aberrant immune response with loss of tolerance to many antigens. Objective: This paper tries to address whether there is any value to test for auto-antibodies in such patients. Methods: 60 patients with inflammatory bowel disease unclassified participated in the study. Auto-antibodies to nuclear antigen, intestin...
متن کاملMCM-2, Ki-67 and PCNA protein expressions in pT3G2 colorectal cancer indicated lymph node involvement.
BACKGROUND The rate of cancer cell growth depends on proliferative activity and on the tumor cell death rate. The study objective was to assess the expressions of Ki-67, PCNA and MCM2 in colorectal cancer and to analyze the correlation between the expressions and chosen anatomo-clinical parameters (patient's age, tumor location, lymph node metastases). PATIENTS AND METHODS The study material ...
متن کاملExpression of p53 and Ki-67 as prognostic factors for survival of men with colorectal cancer.
In patients with colorectal cancer (CRC) several independent prognostic factors are well-supported in the literature, including TNM stage, histological type and grade, and serum levels of carcinoembryonic antigen (CEA). All cancer cells express high levels of tissue proliferation markers, such as Ki-67 and p53, which are currently considered prognostic markers for patients with several types of...
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ژورنال
عنوان ژورنال: European Journal of Cancer Supplements
سال: 2006
ISSN: 1359-6349
DOI: 10.1016/j.ejcsup.2006.04.129